A recent study published in the Journal of Chemical Education highlights a new lab experiment that gives first-semester organic chemistry students at Central College hands-on experience by synthesizing a compound found in common allergy medicine.

Central researchers were lead author and associate professor of chemistry Jay Wackerly, associate professor of chemistry James Dunne, and professor of chemistry James Shriver. They developed a streamlined method to create diphenhydramine, an ingredient in many over-the-counter medications. The lab was designed to reinforce classroom concepts while helping students build practical skills used in real-world chemistry.

The study emphasizes how thoughtful curriculum design can improve student engagement and better prepare future health care professionals. The modular structure of the experiment also allows it to be adapted by a wide range of colleges and universities, regardless of available equipment or lab time. The approach benefits students continuing on to a second semester of organic chemistry, as well as pre-health students – many of whom only take one semester of lab – by offering a meaningful capstone experience.